The 2025 NFL season is just days away, and legendary brothers and former QBs Peyton and Eli Manning are returning to call the action. Monday Night Football with Peyton and Eli, also known as the ManningCast, returns for a fifth season on ESPN2 and streaming on the ESPN DTC app.
The Emmy-winning presentation will feature a new set of guests joining the duo throughout the season, with each episode set to begin after 8:00 PM. This year, the ManningCast debuts in Week 1, with an NFC North showdown on September 8 when Caleb Williams and the Chicago Bears host J.J. McCarthy and the Minnesota Vikings.
The Omaha Production has aired 42 telecasts across four seasons with an average of 1.2 million viewers per show. Over the years, the alternate telecast has become a fan favorite due to the Manning brothers’ insight and expressions, and conversations with guests from the world of pop culture. Critically, the ManningCast has achieved two Sports Emmy wins for Outstanding Live Series (2021, 2023), with Peyton scoring two more for Outstanding Personality/Live Event (2022, 2024).
Check out the full 2025 ManningCast Schedule below.
The 2025 Monday Night Football with Peyton and Eli Schedule
All games to stream on the ESPN app.
| NFL Week | Date | Matchup | Network |
| 1 | Sept. 8 | Vikings at Bears | ESPN2 |
| 3 | Sept. 22 | Lions at Ravens | ESPN2 |
| 5 | Oct. 6 | Chiefs at Jaguars | ESPN2 |
| 8 | Oct. 27 | Commanders at Chiefs | ESPN2 |
| 9 | Nov. 3 | Cardinals at Cowboys | ESPN2 |
| 10 | Nov. 10 | Eagles at Packers | ESPN2 |
| 11 | Nov. 17 | Cowboys at Raiders | ESPN2 |
| 12 | Nov. 24 | Panthers at 49ers | ESPN2 |
| 13 | Dec. 1 | Giants at Patriots | ESPN2 |
| 15 | Dec. 15 | Dolphins at Steelers | ESPN2 |
| 18 | Jan. 3 | Doubleheader Saturday: TBD Matchup | ESPN2 |
| Wild Card | Jan. 12 | TBD | ESPN2 |